The Madeleine Oudin Lab
Our lab focuses on two areas. First, we are nterested in dissecting the mechanisms of cancer metastasis and drug resistance. We focus on the role of the tumor microenvironment, specifically on the role of the extracellular matrix, in driving invasion and contributing to resistance to chemotherapy. We are also interested in dissecting the neuronal properties of tumors: both the nerves that innervate the the tumors and the neuronal properties that tumor cells take on as they grow.
We are also investigating how alternative splicing of sodium channels impacts neuronal function and the development of epilepsy. We aim to develop novel therapies for the treatment of neurodevelopmental disorders, such as those caused by mutations in SCN8A.
Learn more about the Oudin lab