Our research is focused on developing molecular movies illustrating how herpesviruses enter cells and how progeny virions get assembled and exit the cells.
As someone who started into research from the clinical care aspect, the dream is always to find something in the lab that can affect how we treat patients.
The ubiquitin proteasome system and autophagy are the primary cellular systems that regulate protein triage and are therefore essential for the maintenance of a balanced proteome.
To elucidate how defective brain-derived neurotrophic factor (BDNF) signaling in the brain leads to diminished appetite control and the emergence of affective disorders.
My ultimate goal is to follow the breadcrumbs and hopefully discover something fundamentally conserved about immune regulation across multiple organ systems.
Research in my laboratory is focused primarily on pattern formation - the developmental processes that determine the morphological features and cell types of tissues, organs and entire organisms.