Member of: The Mitch McVey Lab
I investigate a protein called polymerase theta that participates in an error-prone DNA repair pathway called alternative end-joining. Polymerase theta causes complex mutations in the genome during repair. I am interested in how the structure of polymerase theta influences its function in alternative end-joining. I am also interested in why a cell chooses alternative end-joining over more accurate forms of DNA repair.
BS, Biology, Stonehill College, Easton, MA