The Mitch McVey Lab
We study proteins and pathways that promote repair or tolerance of DNA damage in the model organism, Drosophila melanogaster. Specifically, we are interested in error-prone repair pathways and their relationship to genomic instability. Ultimately, we hope to gain a clearer understanding of how the various repair pathways are regulated by cell cycle and tissue-specific cues in a multicellular organism, and to learn how this regulation changes during development and aging.