Research/Areas of Interest

Dr.Munger's research group investigates the molecular mechanisms that underlie the oncogenic potential of "high-risk" human papillomaviruses (HPVs). These viruses are responsible for nearly all cases of cervical carcinoma and a substantial proportion of other anogenital and oropharyngeal cancers. While cervical cancer incidence has been declining in the United States, the rates of HPV-associated anal and oral cancers are increasing, and overall, HPVs are causin approximately 5% of human cancers, worldwide.

Current prophylactic modalities do not impact disease progression in individuals who are already infected and hence high-risk HPV infections will continue to pose a significant public health burden for the foreseeable future.

Our work aims to elucidate the molecular interactions between the HPV oncoproteins and host cellular pathways, with the goal of identifying novel therapeutic targets and advancing our understanding of virus-induced carcinogenesis.

Education

  • Doctor of Philosophy, University of Zurich, Switzerland, 1986