What It’s Like to Be a PhD Student at Tufts: Q&A with Haley Dame

Haley Dame is a PhD student in the Genetics, Molecular & Cellular Biology program at the Tufts University Graduate School of Biomedical Sciences, working in the lab of Madeleine Oudin, PhD. With a passion for research rooted in curiosity and collaboration, Haley is investigating gene therapy strategies for genetic epilepsy. Her journey at Tufts has been shaped by a strong sense of community, supportive faculty, and the vibrant scientific atmosphere of Boston.

Why did you choose to pursue a PhD?

"During my undergraduate degree at Suffolk University, I fell in love with research. I loved being in the lab, running experiments, and exploring the endless questions that science allows you to ask. That sense of curiosity drove me to pursue a PhD—not only so I could continue doing research, but also to become a better scientist. I wanted to learn how to ask the right questions, design thoughtful experiments, and grow into a leader in the lab."

Why did you choose Tufts for your graduate studies?

"After six years in Boston for undergrad and a post-bacc, I thought I’d move to a new city for my PhD. But during my visit to Tufts, I quickly reconsidered. Every student I met seemed genuinely happy. The environment wasn’t competitive—it was collaborative. The faculty were supportive not just of research, but of helping students reach a wide range of career goals. On top of that, I realized how much I love Boston. Having built such a strong personal and professional community here, I can’t imagine doing a PhD anywhere else. Plus, working in downtown Boston comes with perks—like rooftop drinks with lab mates and exploring all the lunch spots in Chinatown."

What is the focus of your research?

"My research focuses on the development of gene therapy for SCN8A epilepsy. I’ve designed splice-switching antisense oligonucleotides that target the alternative splicing of SCN8A exon 5, with the goal of reducing the effects of this rare but severe genetic disorder. My work is part of a larger effort to develop genetic therapeutics for neurological diseases."

How would you describe your experience in the program?

"There are definitely ups and downs during a PhD, but I’ve truly enjoyed the journey—largely thanks to the people. My lab mates in the Oudin and Dulla labs are kind, supportive, and genuinely fun to work with. Tufts has fostered a collaborative and non-competitive environment that makes it easy to build friendships and grow as a scientist. I’ve also been involved in the Graduate Student Council, which has connected me with students across programs and shown me how many great events Tufts hosts to bring us together. The faculty are another highlight—they’re approachable, engaged, and go out of their way to help students thrive."

What do you love most about the Tufts community?

"The people. Both the students and faculty are amazing. It’s a place where you feel supported and encouraged—not just academically, but personally. Having a strong community is so important during grad school, and I’ve found that at Tufts."

What has been your proudest accomplishment so far?

"I’ve been fortunate to attend and present at conferences across the country and abroad—from Barcelona to Utah and Los Angeles. This past year, I gave talks at both a Gordon Conference and the American Epilepsy Society Conference. Presenting my thesis work at those events was a major milestone for me, and I’m proud of how far I’ve come. I’m excited to continue sharing my research with the broader scientific community."

How do you recharge outside of the lab?

"Now that the weather is nice, I’ve been loving patio season—trying new spots in Boston and Somerville with friends. I also spend a lot of time reading outside, which has been really relaxing and restorative."

What are your goals after graduation?

"I hope to continue researching genetic therapeutics for neurological disorders. I’m open to doing this either in a postdoc or transitioning directly into industry. Ultimately, I want to help bring novel therapeutics from the lab to patients."

What should prospective students know about Tufts?

"There are really good people at Tufts. The faculty are genuinely invested in your success and will cheer you on the whole way. The students are thoughtful, collaborative, and kind. Having a supportive environment during your PhD is just as important as the research itself, and Tufts provides both."

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