Research/Areas of Interest
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and cognitive impairment. The pathological hallmarks include extracellular plaques composed of amyloid beta and intracellular neurofibrillary tangles of hyperphosphorylated tau. Recent genome-wide association studies have identified >20 susceptibility genes implicating the immune system, lipid metabolism, and synaptic function in AD. I am investigating the association of three prominent gene variants and their contribution to late-onset AD. I aim to uncover the interaction between these risk variants in the major CNS cell types of the brain via human iPSC differentiated into neurons, microglia, and astrocytes.
Education
BA, Neuroscience, Boston University, Boston, MA