Research/Areas of Interest

My lab studies cartilage development and cartilage-related diseases using interdisciplinary approaches. Abnormality in cartilage development leads to defects in skeletogenesis. In adults, destruction of the articular cartilage on the surface of the bone is the hallmark of arthritis, which is marked by joint inflammation and pain. A major focus is to investigate molecular and cellular changes in the initiation and progression of osteoarthritis. By interrogating the metabolic control of developmental phases in cartilage growth, we gain important insights into bone and joint regeneration for the treatment of skeletal defects and osteoarthritis.

Education

  • Doctor of Philosophy, Columbia University, New York, United States
  • Masters of Philosophy, Columbia University, New York, United States
  • Masters of Science, Tsinghua University, Beijing, China
  • Bachelor of Science, China Agricultural University, Haidian, China