Research/Areas of Interest:
My research focuses on the study of aging in the context of cellular metabolism, particularly as it pertains to the process known as cellular senescence. Cellular senescence is a stress response by which cells adopt a state of permanent mitotic arrest. More than simple arrest, the senescent phenotype is complex and includes a senescence-associated secretory phenotype (SASP) that leads to secretion of multiple biologically-active molecules – including proinflammatory cytokines, matrix metalloproteinases, and growth factors – that can have potent effects on the tissue microenvironment. I hope to reveal new insights regarding the nature of cellular senescence and offer alternative avenues for intervention for associated disorders, such as cancer, diabetes, and aging.
Education
- BS, University of Minnesota, USA
- MS, Illinois State University, USA
- PhD, University of California - Irvine, USA