Pablo Argueso

Research/Areas of Interest

Dr. Argüeso specializes in corneal diseases and has achieved international recognition for his work studying ocular surface biology. His research focuses on the structure and function of the glycocalyx—a carbohydrate-rich layer lining the surface of eukaryotic cells. His laboratory has developed innovative methods clearly demonstrating the importance of mucins in forming a protective biofilm on epithelial and endothelial cell surfaces. His studies have also uncovered important roles for galectins in the maintenance of ocular surface integrity and immune cell homeostasis, yielding crucial insight into defense mechanisms averting environmental insult and infection. More recent research from his laboratory seeks to define the role of the glycome on pathological remodeling processes associated with wound repair and limbal stem cell deficiency.