Molecular Microbiology Student Publications
Publication in peer-reviewed journals is a very important part of graduate training. Publications by Molecular Microbiology students over the past five years are listed below. The names of student authors are in bold font.
2024
Davis KP, Morales Y, Ende RJ, Peters R, McCabe AL, Mecsas J, Aldridge BB.. 2024. Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses. mBio. 2024 Feb 16:e0015924. doi: 10.1128/mbio.00159-24. Abstract
Day AW, Kumamoto CA. 2024. Selection of ethanol tolerant strains of Candida albicans by repeated ethanol exposure results in strains with reduced susceptibility to fluconazole. PLoS One. Feb 20;19(2):e0298724. doi: 10.1371/journal.pone.0298724. Abstract
2023
Ahn YM, Lavin RC, Tan S, Freundlich JS. 2023. Liquid chromatography-mass spectrometry-based protocol to measure drug accumulation in Mycobacterium tuberculosis and its host cell. STAR Protoc. 2023 Jan 3;4(1):101971. Abstract
Bourgeois J, Camilli A. 2023. High-throughput mutant screening in Vibrio cholerae via transposon sequencing. Cold Spring Harb Protoc. Mar 17. doi: 10.1101/pdb.prot108185. Abstract
Bourgeois J, Camilli A. 2023. High-throughput mutant screening via transposon sequencing. Cold Spring Harb Protoc. Mar 17. doi: 10.1101/pdb.prot107867. Abstract
Chen Y, Quirk NF, Tan S. 2023. Shining a light on bacterial environmental cue integration and its relation to metabolism. Mol Microbiol. Jul;120(1):71-74. doi: 10.1111/mmi.15065. Abstract
Day AW, Kumamoto CA. 2023. Interplay between host and Candida albicans. PLoS Pathog.Sep 14;19(9):e1011607. doi: 10.1371/journal.ppat.1011607. Abstract
Gaucherand L, Iyer A, Gilabert I, Rycroft CH, Gaglia MM.2023. Cut site preference allows influenza A virus PA-X to discriminate between host and viral mRNAs Nat Microbiol. Jun 22. doi: 10.1038/s41564-023-01409-8. Abstract
Gladden-Young A. 2023. Diverse pathways toward a cure. iScience. Feb 16;26(3):106052. doi: 10.1016/j.isci.2023.106052. Abstract
Gwynne PJ, Stocks K-LK, Karozichian ES, Pandit A, Hu LT. 2023. Metabolic modeling predicts unique drug targets in Borrelia burgdorferi. mSystems. Oct 19:e0083523. doi: 10.1128/msystems.00835-23. Abstract
Hsueh BY, Chen G, Yoon SH, Demey LM, O'Hara BJ, Rhoades CR, DiRita VJ, Ng WL, Waters CM. 2023. Activation of a Vibrio cholerae CBASS anti-phage system by quorum sensing and folate depletion. mBio. Aug 25:e0087523. doi: 10.1128/mbio.00875-23. Abstract
Phelan JP, Bourgeois JS, McCarthy JE, Hu LT. 2023. A putative xanthine dehydrogenase is critical for Borrelia burgdorferi survival in ticks and mice. Microbiology. 169(1). doi: 10.1099/mic.0.001286. Abstracta
Ramirez JM, Calderon-Zavala AC, Balaram A, Heldwein EE. 2023. In vitro reconstitution of herpes simplex virus 1 fusion identifies low pH as a fusion co-trigger. mBio. Oct 24:e0208723. doi: 10.1128/mbio.02087-23. Abstract
Ribis JW, Melo L, Shrestha S, Giacalone D, Rodriguez EE, Shen A, Rohlfing A. 2023. Single-spore germination analyses reveal that calcium released during Clostridioides difficile germination functions in a feedforward loop. mSphere. Jun 20:e0000523. doi: 10.1128/msphere.00005-23. Abstract
Shrestha S, Taib N, Gribaldo S, Shen A.. 2023. Diversification of division mechanisms in endospore-forming bacteria revealed by analyses of peptidoglycan synthesis in Clostridioides difficile. Nat Commun. Dec 2;14(1):7975. doi: 10.1038/s41467-023-43595-3. Abstract
Van N, Degefu YN, Leus PA, Larkins-Ford J, Klickstein J, Maurer FP, Stone D, Poonawala H, Thorpe CM, Smith TC 2nd, Aldridge BB. 2023. Novel synergies and isolate specificities in the drug interaction landscape of Mycobacterium abscessus. Antimicrob Agents Chemother. Jun 6:e0009023. doi: 10.1128/aac.00090-23. Abstract
Wu SC, Grace M, Munger K. 2023. The HPV8 E6 protein targets the Hippo and Wnt signaling pathways as part of its arsenal to restrain keratinocyte differentiation. mBio. Sep 7:e0155623. doi: 10.1128/mbio.01556-23. Abstract
Xu S, Mo D, Rizvi FZ, Rosa JP, Ruiz J, Tan S, Tweten RK, Leong JM, Adams W. 2023. Pore-forming activity of S. pneumoniae pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin. Infect Immun. Sep 14;91(9):e0021323. doi: 10.1128/iai.00213-23.. Abstract
2022
Arman W, Munger K. 2022. Mechanistic contributions of lncRNAs to cellular signaling pathways crucial to the lifecycle of human papillomaviruses. Viruses. Nov 3;14(11):2439. doi: 10.3390/v14112439. Abstract
Barrasso K, Chac D, Debela MD, Geigel C, Steenhaut A, Rivera Seda A, Dunmire CN, Harris JB, Larocque RC, Midani FS, Qadri F, Yan J, Weil AA, Ng WL. 2022. Impact of a human gut microbe on Vibrio cholerae host colonization through biofilm enhancement. Elife. Mar 28;11:e73010. doi: 10.7554/eLife.73010. Abstract
Chung ES, Johnson WC, Aldridge BB. 2022. Types and functions of heterogeneity in mycobacteria. Nat Rev Microbiol. Apr 1. doi: 10.1038/s41579-022-00721-0. Abstract
Day AW, Kumamoto CA. 2022. Gut microbiome dysbiosis in alcoholism: Consequences for health and recovery. Front Cell Infect Microbiol. Mar 3;12:840164. doi: 10.3389/fcimb.2022.840164. Abstract
Donnelly ML, Shrestha S, Ribis JW, Kuhn P, Krasilnikov M, Alves Feliciano C, Shen A. 2022. Development of a dual-fluorescent-reporter system in Clostridioides difficile reveals a division of labor between virulence and transmission gene expression. mSphere. 31:e0013222. doi: 10.1128/msphere.00132-22. Abstract
Dumitrescu DG, Gordon EM, Kovalyova Y, Seminara AB, Duncan-Lowey B, Forster ER, Zhou W, Booth CJ, Shen A, Kranzusch PJ, Hatzios SK. 2022. A microbial transporter of the dietary antioxidant ergothioneine. Cell. Nov 3:S0092-8674(22)01323-X. doi: 10.1016/j.cell.2022.10.008. Abstract
Forster ER, Yang X, Tai AK, Hang HC, Shen A. 2022. Identification of a bile acid-binding transcription factor in Clostridioides difficile using chemical proteomics. ACS Chem Biol. Oct 24. doi: 10.1021/acschembio.2c00463. Abstract
Gaucherand L, Gaglia MM. 2022. The role of viral RNA degrading factors in shutoff of host gene expression. Annu Rev Virol. Jun 7. doi: 10.1146/annurev-virology-100120-012345. Abstract
Giacalone D, Yap RE, Ecker AMV, Tan S. 2020. PrrA modulates Mycobacterium tuberculosis response to multiple environmental cues and is critically regulated by serine/threonine protein kinases. PLoS Genet. Aug 1;18(8):e1010331. doi: 10.1371/journal.pgen.1010331. Abstract
Huo W, Busch LM, Hernandez-Bird J, Hamami E, Marshall CW, Geisinger E, Cooper VS, van Opijnen T, Rosch JW, Isberg RR. 2022. Immunosuppression broadens evolutionary pathways to drug resistance and treatment failure during Acinetobacter baumannii pneumonia in mice. Nat Microbiol. doi: 10.1038/s41564-022-01126-8. Abstract
Junier A, Weeks A, Alcaraz Y, Kumamoto CA. 2022. Bypass of Dfi1 regulation of Candida albicans invasive filamentation by iron limitation. mSphere. Feb 2:e0077921. doi: 10.1128/msphere.00779-21. Abstract
Kevorkian YL, MacGilvary NJ, Giacalone D, Johnson C, Tan S. 2022. Rv0500A is a transcription factor that links Mycobacterium tuberculosis environmental response with division and impacts host colonization. Mol Microbiol. Feb 15. doi: 10.1111/mmi.14886. Abstract
Larkins-Ford J, Aldridge BB. 2022. Advances in the design of combination therapies for the treatment of tuberculosis. Expert Opin Drug Disc. Dec 20. doi: 10.1080/17460441.2023.2157811. Abstract
Larkins-Ford J, Degefu YN, Van N, Sokolov A, Aldridge BB. 2022. Design principles to assemble drug combinations for effective tuberculosis therapy using interpretable pairwise drug response measurements. Cell Rep Med. Sep 20;3(9):100737. doi: 10.1016/j.xcrm.2022.100737. Abstract
Lavin RC, Tan S. 2022. Spatial relationships of intra-lesion heterogeneity in Mycobacterium tuberculosis microenvironment, replication status, and drug efficacy. PLoS Pathog. Mar 28;18(3):e1010459. doi: 10.1371/journal.ppat.1010459. Abstract
O'Hara BJ, Alam M, Ng WL. 2022. The Vibrio cholerae Seventh Pandemic Islands act in tandem to defend against a circulating phage. PLoS Genet. 2022 Aug 26;18(8):e1010250. doi: 10.1371/journal.pgen.1010250. Abstract
Pataki Z, Rebolledo Viveros A, Heldwein EE. 2022. Herpes simplex virus 1 entry glycoproteins form complexes before and during membrane fusion. mBio. Aug 16:e0203922. doi: 10.1128/mbio.02039-22. Abstract
Pataki Z, Sanders EK, Heldwein EE. 2022. A surface pocket in the cytoplasmic domain of the herpes simplex virus fusogen gB controls membrane fusion. PLoS Pathog. Jun 29;18(6):e1010435. doi: 10.1371/journal.ppat.1010435. Abstract
Pereira MJ, Wager B, Garrigues RJ, Gerlach E, Quinn JD, Dowdell AS, Osburne MS, Zückert WR, Kraiczy P, Garcia BL, Leong JM. 2022. Lipoproteome screening of the Lyme disease agent identifies inhibitors of antibody-mediated complement killing. Proc Natl Acad Sci USA. Mar 29;119(13):e2117770119. doi: 10.1073/pnas.2117770119. Abstract
Tabtieng T, Lent RC, Kaku M, Monago Sanchez A, Gaglia MM. 2022. Caspase-mediated regulation and cellular heterogeneity of the cGAS/STING pathway in Kaposi's sarcoma-associated herpesvirus infection. mBio. Oct 18:e0244622. doi: 10.1128/mbio.02446-22. Abstract
Tan X, Lin YP, Pereira MJ, Castellanos M, Hahn BL, Anderson P, Coburn J, Leong JM, Chaconas G. 2022. VlsE, the nexus for antigenic variation of the Lyme disease spirochete, also mediates early bacterial attachment to the host microvasculature under shear force. PLoS Pathog. 18(5):e1010511. doi: 10.1371/journal.ppat.1010511. Abstract
2021
Blakemore RJ, Burnett C, Swanson C, Kharytonchyk S, Telesnitsky A, Munro JB. 2021. Stability and conformation of the dimeric HIV-1 genomic RNA 5'UTR. Biophys J. 120: 4874-4890. Abstract
Flowers LJ, Hu S, Shrestha A, Martinot AJ, Leong JM, Osburne MS. 2021. Citrobacter rodentium lysogenized with a Shiga toxin-producing phage: A murine model for shiga toxin-producing E. coli infection. Methods Mol Biol. 2291:381-397. doi: 10.1007/978-1-0716-1339-9_19. Abstract
Giacalone D, Huang L, Tan S. 2021. Exploiting fluorescent proteins to understand Mycobacterium tuberculosis biology. Methods Mol Biol. 2314:365-383. Abstract
Larkins-Ford J, Greenstein T, Van N, Degefu YN, Olson MC, Sokolov A, Aldridge BB. 2021. Systematic measurement of combination-drug landscapes to predict in vivo treatment outcomes for tuberculosis. Cell Syst. Aug 21:S2405-4712(21)00292-1. doi: 10.1016/j.cels.2021.08.004. Abstract
Lavin RC, Johnson C, Ahn YM, Kremiller KM, Sherwood M, Patel JS, Pan Y, Russo R, MacGilvary NJ, Giacalone D, Kevorkian YL, Zimmerman MD, Glickman JF, Freundlich JS, Tan S. 2021. Targeting Mycobacterium tuberculosis response to environmental cues for the development of effective antitubercular drugs. PLoS Biol. Jul 28;19(7):e3001355. doi: 10.1371/journal.pbio.3001355. Abstract
Joma BH, Siwapornchai N, Vanguri VK, Shrestha A, Roggensack SE, Davidson BA, Tai AK, Hakansson AP, Meydani SN, Leong JM, Bou Ghanem EN. 2021. A murine model for enhancement of Streptococcus pneumoniae pathogenicity upon viral infection and advanced age. Infect Immun. 24:IAI.00471-20. doi: 10.1128/IAI.00471-20. Abstract
Levene RE, Shrestha SD, Gaglia MM. 2021. The influenza A virus host shutoff factor PA-X is rapidly turned over in a strain-specific manner. J Virol. 27:JVI.02312-20. doi: 10.1128/JVI.02312-20. Abstract
Lim ANW, Yen M, Seed KD, Lazinski DW, Camilli A . 2021. A tail fiber protein and a receptor-binding protein mediate ICP2 bacteriophage interactions with Vibrio cholerae OmpU. J Bacteriol. Apr 19:JB.00141-21. doi: 10.1128/JB.00141-21. Abstract
Markey L, Pugliese A, Tian T, Roy F, Lee K, Kumamoto CA. 2021. Decreased ecological resistance of the gut microbiota in response to clindamycin challenge in mice colonized with the fungus Candida albicans. mSphere. 6: e00982-20. doi: 10.1128/mSphere.00982-20. Abstract
Matthews AJ, Rowe HM, Rosch JW, Camilli A. 2021. A Tn-seq screen of Streptococcus pneumoniae uncovers DNA repair as the major pathway for desiccation tolerance and transmission. Infect Immun. 24:IAI.00713-20. doi: 10.1128/IAI.00713-20. Abstract
Patel P, O'Hara BJ, Aunins E, Davis KM. 2021. Modifying TIMER to generate a slow-folding DsRed derivative for optimal use in quickly-dividing bacteria. PLoS Pathog. 17(7):e1009284. doi: 10.1371/journal.ppat.1009284. Abstract
Wu SC, Münger K. 2021. Role and clinical utility of cancer/testis antigens in head and neck squamous cell carcinoma. Cancers. Nov 14;13(22):5690. doi: 10.3390/cancers13225690. Abstract
Zhang M, McEwen JM, Sjoblom NM, Kotewicz KM, Isberg RR, Scheck RA. 2021. Members of the Legionella pneumophila Sde family target tyrosine residues for phosphoribosyl-linked ubiquitination. RSC Chem Biol. 2: 1509-1519.doi: 10.1039/d1cb00088h. Abstract
2020
Anand IS, Choi WY, Isberg RR. 2020. Components of the endocytic and recycling trafficking pathways interfere with the integrity of the Legionella-containing vacuole. Cell Microbiol. 15:e13151. doi: 10.1111/cmi.13151. Abstract
Anand I, Choi W, Isberg RR. 2020. The vacuole guard hypothesis: how intravacuolar pathogens fight to maintain the integrity of their beloved home. Curr Opin Microbiol. 54: 51-58. Abstract
Barrasso K, Watve S, Simpson CA, Geyman LJ, van Kessel JC, Ng WL. 2020. Dual-function quorum-sensing systems in bacterial pathogens and symbionts. PLoS Pathog. 16:e1008934. doi: 10.1371/journal.ppat.1008934. Abstract
Bernard Q, Phelan JP, Hu LT. 2020. Controlling Lyme disease: New paradigms for targeting the tick-pathogen-reservoir axis on the horizon. Front Cell Infect Microbiol. 10:607170. doi: 10.3389/fcimb.2020.607170. Abstract
Bhalla M, Simmons SR, Abamonte A, Herring SE, Roggensack SE, Bou Ghanem EN. 2020. Extracellular adenosine signaling reverses the age-driven decline in the ability of neutrophils to kill Streptococcus pneumoniae. Aging Cell 13:e13218. Abstract
Bourgeois J, Lazinski DW, Camilli A. 2020. Identification of spacer and protospacer sequence requirements in the Vibrio cholerae Type I-E CRISPR/Cas System. mSphere 5(6):e00813-20. doi: 10.1128/mSphere.00813-20. Abstract
Bulow U, Govindan R, Munro JB. 2020. Acidic pH triggers lipid mixing mediated by Lassa virus GP. Viruses 12(7) pii: E716. doi: 10.3390/v12070716. Abstract
Clark SA, Thibault D, Shull LM, Davis KM, Aunins E, van Opijnen T, Isberg R. 2020. Topologically correct synthetic reconstruction of pathogen social behavior found during Yersinia growth in deep tissue sites. Elife. 9. pii: e58106. doi: 10.7554/eLife.58106. Abstract
Cornacchione LP, Hu LT. 2020. Hydrogen peroxide-producing pyruvate oxidase from Lactobacillus delbrueckii is catalytically activated by phosphotidylethanolamine. BMC Microbiol. 20(1):128. doi: 10.1186/s12866-020-01788-6. Abstract
Das DK, Bulow U, Diehl WE, Durham ND, Senjobe F, Chandran K, Luban J, Munro JB. 2020. Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding. PLoS Biol. 18(2):e3000626. doi: 10.1371/journal.pbio.3000626. Abstract
de la Puebla HB, Giacalone D, Cooper A, Shen A. 2020. Role of SpoIVA ATPase motifs during Clostridioides difficile sporulation. J Bacteriol. 17:JB.00387-20. Abstract
Donnelly ML, Forster ER, Rohlfing AE, Shen A. 2020. Differential effects of "resurrecting" Csp pseudoproteases during Clostridioides difficile spore germination. Biochem J. pii: BCJ20190875. doi: 10.1042/BCJ20190875. Abstract
Durham ND, Howard AR, Govindan R, Senjobe F, Fels JM, Diehl WE, Luban J, Chandran K, Munro JB. 2020. Real-time analysis of individual Ebola virus glycoproteins reveals pre-fusion, entry-relevant conformational dynamics. Viruses. 12(1). pii: E103. doi: 10.3390/v12010103. Abstract
Koenigsberg AL, Pitts JD, Heldwein EE. 2020. Identification of buffer conditions for optimal thermostability and solubility of herpesviral protein UL37 using the thermofluor assay. Bio Protoc. 10(12):e3662. doi: 10.21769/BioProtoc.3662.. Abstract
Markey L, Hooper A, Melon LC, Baglot S, Hill MN, Maguire J, Kumamoto CA. 2020. Colonization with the commensal fungus Candida albicans perturbs the gut-brain axis through dysregulation of endocannabinoid signaling. Psychoneuroendocrinology 121: 104808. Abstract
Metrick CM, Koenigsberg AL, Heldwein EE. 2020. Conserved outer tegument component UL11 from herpes simplex virus 1 is an intrinsically disordered, RNA-binding protein. mBio. 11: pii: e00810-20. doi: 10.1128/mBio.00810-20. Abstract
Nguyen GT, Shaban L, Mack M, Swanson KD, Bunnell SC, Sykes DB, Mecsas J. 2020. SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst. Elife pii: e56656. doi: 10.7554/eLife.56656. Abstract
Oliveira PH, Ribis JW, Garrett EM, Trzilova D, Kim A, Sekulovic O, Mead EA, Pak T, Zhu S, Deikus G, Touchon M, Lewis-Sandari M, Beckford C, Zeitouni NE, Altman DR, Webster E, Oussenko I, Bunyavanich S, Aggarwal AK, Bashir A, Patel G, Wallach F, Hamula C, Huprikar S, Schadt EE, Sebra R, van Bakel H, Kasarskis A, Tamayo R, Shen A, Fang G. 2020. Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis. Nat Microbiol. 5(1):166-180. Abstract
Romo JA, Markey L, Kumamoto CA. 2020. Lipid species in the GI tract are increased by the commensal fungus Candida albicans and decrease the virulence of Clostridioides difficile. J Fungi pii: E100. doi: 10.3390/jof6030100. Abstract
Shaban L, Nguyen GT, Mecsas-Faxon BD, Swanson KD, Tan S, Mecsas J. 2020. Yersinia pseudotuberculosis YopH targets SKAP2-dependent and independent signaling pathways to block neutrophil antimicrobial mechanisms during infection. PLoS Pathog. 16: e1008576. Abstract
Siwapornchai N, Lee JN, Tchalla EYI, Bhalla M, Yeoh JH, Roggensack SE, Leong JM, Bou Ghanem EN. 2020. Extracellular adenosine enhances the ability of PMNs to kill Streptococcus pneumoniae by inhibiting IL-10 production. J Leukoc Biol. doi: 10.1002/JLB.4MA0120-115RR. Abstract
Smith TC 2nd, Pullen KM, Olson MC, McNellis ME, Richardson I, Hu S, Larkins-Ford J, Wang X, Freundlich JS, Ando DM, Aldridge BB. 2020. Morphological profiling of tubercle bacilli identifies drug pathways of action. Proc Natl Acad Sci USA Jul 17:202002738. doi: 10.1073/pnas.2002738117.Jul 17:202002738. doi: 10.1073/pnas.2002738117. Abstract
Watve S, Barrasso K, Jung SA, Davis KJ, Hawver LA, Khataokar A, Palaganas RG, Neiditch MB, Perez LJ, Ng WL. 2020. Parallel quorum-sensing system in Vibrio cholerae prevents signal interference inside the host. PLoS Pathog. 16:(2):e1008313. doi: 10.1371/journal.ppat.1008313. Abstract
Yang X, Forster ER, Darabedian N, Kim AT, Pratt MR, Shen A, Hang HC. 2020. Translation of microbiota short-chain fatty acid mechanisms affords anti-infective acyl-salicylic acid derivatives. ACS Chem Biol. 15(5):1141-1147.Abstract
2019
Burgain A, Pic É, Markey L, Tebbji F, Kumamoto CA, Sellam A. 2019. A novel genetic circuitry governing hypoxic metabolic flexibility, commensalism and virulence in the fungal pathogen Candida albicans. PLos Pathog. 15: e1007823. Abstract
Cornacchione LP, Klein BA, Duncan MJ, Hu LT. 2019. Interspecies inhibition of Porphyromonas gingivalis by yogurt-derived Lactobacillus delbrueckii require active pyruvate oxidase. Appl Environ Microbiol. 85(18):e01271-19. doi: 10.1128/AEM.01271-19. . Abstract
Davis KM, Krupp J, Clark S, Isberg RR. 2019. Iron-sulfur cluster repair contributes to Y. pseudotuberculosis survival within deep tissues. Infect Immun. 87(10):e00533-19. doi: 10.1128/IAI.00533-19. Abstract
Gaucherand L, Porter BK, Levene RE, Price EL, Schmaling SK, Rycroft CH, Kevorkian Y, McCormick C, Khaperskyy DA, Gaglia MM. 2019. The Influenza A virus endoribonuclease PA-X usurps host mRNA processing machinery to limit host gene expression. Cell Rep. 27: 776-792. Abstract
Geisinger E, Huo W, Hernandez-Bird J, Isberg RR. 2019. Acinetobacter baumannii: Envelope determinants that control drug resistance, virulence, and surface variability. Annu Rev Microbiol. 73: 481-506. Abstract
Holloway JR, Williams ZH, Freeman MM, Bulow U, Coffin JM. 2019. Gorillas have been infected with the HERV-K (HML-2) endogenous retrovirus much more recently than humans and chimpanzees. Proc Natl Acad Sci USA. 116: 1337-1346. Abstract
Howard AR, Munro JB. 2019. Developments in single-molecule and single-particle fluorescence-based approaches for studying viral envelope glycoprotein dynamics and membrane fusion. Adv Virus Res. 104: 1230146. Abstract
Ma S, Jaipalli S, Larkins-Ford J, Lohmiller J, Aldridge BB, Sherman DR, Chandrasekaran S. 2019. Transcriptomic signatures predict regulators of drug synergy and clinical regimen efficacy against tuberculosis. mBio 10: e02627-19. Abstract
MacGilvary NJ, Kevorkian YL, Tan S. 2019. Potassium response and homeostasis in Mycobacterium tuberculosis modulates environmental adaptation and is important for host colonization. PLoS Pathog. 15(2):e1007591. Abstract
Phelan JP, Kern A, Ramsey ME, Lundt ME, Sharma B, Lin T, Gao L, Norris SJ, Hyde JA, Skare JT, Hu LT. 2019. Genome-wide screen identifies novel genes required for Borrelia burgdorferi survival in its Ixodes tick vector. PLoS Pathog. 15: e1007644. Abstract
Rohlfing AE, Eckenroth BE, Forster ER, Kevorkian Y, Donnelly ML, Benito de la Puebla H, Doublié S, Shen A. 2019. The CspC pseudoprotease regulates germination of Clostridioides difficile spores in response to multiple environmental signals. PLoS Genet. 15: e1008224. Abstract
Sekulovic O, Bourgeois J, Shen A, Camilli A. 2019. Expanding the repertoire of conservative site-specific recombination in Clostridioides difficile. Anaerobe. Dec;60:102073. doi: 10.1016/j.anaerobe.2019.102073. Abstract
Silver RJ, Paczosa MK, McCabe AL, Balada-Llasat JM, Baleja JD, Mecsas J. 2019. Amino acid biosynthetic pathways are required for Klebsiella pneumoniae growth in immunocompromised lungs and are druggable targets during infection. Antimicrob Agents Chemother. 25;63(8):e02674-18. doi: 10.1128/AAC.02674-18. Abstract
Sol A, Lipo E, de Jesús-Díaz DA, Murphy C, Devereux M, Isberg RR. 2019. Legionella pneumophila translocated translation inhibitors are required for bacterial-induced host cell cycle arrest. Proc Natl Acad Sci USA. 116: 3221-3228. Abstract
Thibault D, Jensen PA, Wood S, Qabar C, Clark S, Shainheit MG, Isberg RR, van Opijnen T. 2019. Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes. Nat Commun. 10(1)5729 doi: 10.1038/s41467-019-13719-9. Abstract
Tscherner M, Giessen TW, Markey L, Kumamoto CA, Silver PA. 2019. A synthetic system that senses Candida albicans and inhibits virulence factors. ACS Synth Biol. 8: 434-444. Abstract