MD/PhD Student Publications

Publication in peer-reviewed journals is a very important part of graduate training. Publications by MSTP students over the past five years are listed below. The names of student authors are in bold font.

2024

Barrios-Camacho CM, Zunitch MJ, Louie JD, Jang W, Schwob JE. 2024. An in vitro model of acute horizontal basal cell activation reveals gene regulatory networks underlying the nascent activation phase.Stem Cell Reports. Jul 12:S2213-6711(24)00191-7. doi: 10.1016/j.stemcr.2024.06.011. Abstract

Bayer AL, Padilla-Rolon D, Smolgovsky S, Hinds P, Alcaide P. 2024. Deletion of MyD88 in T-cells improves anti-tumor activity in melanoma. Am J Pathol. Mar 3:S0002-9440(24)00083-X. doi: 10.1016/j.ajpath.2024.02.012. Abstract

Biwer LA, Man JJ, Camarda ND, Carvajal BV, Karumanchi SA, Jaffe IZ. 2024. Prior exposure to experimental preeclampsia increases atherosclerotic plaque inflammation in atherogenic mice. Arterioscler Thromb Vasc Biol. Mar 7. doi: 10.1161/ATVBAHA.123.320474. Abstract

Bottom-Tanzer S, Corella S, Meyer J, Sommer M, Bolaños L, Murphy T, Quiñones S, Heiney S, Shtrahman M, Whalen M, Oren R, Higley MJ, Cardin JA, Noubary F, Armbruster M, Dulla C. 2024. Cereb Cortex. Jan 31;34(2):bhae038. doi: 10.1093/cercor/bhae038. Abstract

Bigham Z, Holder EX, Rodday AM, Breeze J, Nelson KP, Palmer JR, Freund KM, Bertrand KA. 2024. Lifecourse growth and development determinants of mammographic density in Black women. Cancer Epidemiol Biomarkers Prev. Aug 2. doi: 10.1158/1055-9965.EPI-24-0494. Abstract

Camarda ND, Ibarrola J, Biwer LA, Jaffe IZ. 2024. Mineralocorticoid receptors in vascular smooth muscle: Blood pressure and beyond. Hypertension. Mar 1. doi: 10.1161/HYPERTENSIONAHA.123.21358. Abstract

Camarda ND, Lu Q, Meola DM, Man JJ, Song Z, Travers RJ, Lopez KE, Powers SN, Papanastasiou M, DeRuff KC, Mullahoo J, Egri SB, Davison D, Sebastiani P, Eblen ST, Buchsbaum R, Huggins GS, London CA, Jaffe JD, Upshaw JN, Yang VK, Jaffe IZ. 2024. Identifying mitigating strategies for endothelial cell dysfunction and hypertension in response to VEGF receptor inhibitors. Clin Sci (Lond). Sep 18;138(18):1131-1150. doi: 10.1042/CS20240537. Abstract.

Champroux A, Tang Y, Dickson DA, Meng A, Harrington A, Liaw L, Marzi M, Nicassio F, Schlaeger TM, Feig LA. 2024. Transmission of reduced levels of miR-34/449 from sperm to preimplantation embryos is a key step in the transgenerational epigenetic inheritance of the effects of paternal chronic social instability stress. Epigenetics. Dec;19(1):2346694. doi: 10.1080/15592294.2024.2346694. Abstract

Davis KP, Morales Y, Ende RJ, Peters R, McCabe AL, Mecsas J, Aldridge BB.. 2024. Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses. mBio. 2024 Feb 16:e0015924. doi: 10.1128/mbio.00159-24. Abstract

Gao S, Guan H, Bloomer H, Wich D, Song D, Khirallah J, Ye Z, Zhao Y, Chen M, Xu C, Liu L, Xu Q. 2024. Harnessing non-Watson-Crick's base pairing to enhance CRISPR effectors cleavage activities and enable gene editing in mammalian cells. Proc Natl Acad Sci U S A. Jan 9;121(2):e2308415120. doi: 10.1073/pnas.2308415120.  Abstract

Hisey JA, Radchenko EA, Mandel NH, McGinty RJ, Matos-Rodrigues G, Rastokina A, Masnovo C, Ceschi S, Hernandez A, Nussenzweig A, Mirkin SM.. 2024. Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures. Nucleic Acids Res. Feb 21:gkae124. doi: 10.1093/nar/gkae124. Abstract

Klickstein JA, Johnson MA, Antonoudiou P, Maguire J, Paulo JA, Gygi SP, Weihl C, Raman M. 2024. ALS-related p97 R155H mutation disrupts lysophagy in iPSC-derived motor neurons. Stem Cell Reports. 2024 Jan 20:S2213-6711(24)00005-5. doi: 10.1016/j.stemcr.2024.01.002. Abstract

Louie JD, Barrios-Camacho CM, Bromberg BH, Hintschich CA, Schwob JE. 2024. Spatiotemporal dynamics exhibited by horizontal basal cells reveal a pro-neurogenic pathway during injury-induced olfactory epithelium regeneration. iScience. 2024 Mar 27;27(5):109600. doi: 10.1016/j.isci.2024.109600. Abstract

Travers RJ, Stepanian A, Jaffe I. 2024. Endothelium as a source of cardiovascular toxicity from antitumor kinase inhibitors. Arterioscler Thromb Vasc Biol. Aug 15. doi: 10.1161/ATVBAHA.124.319864. Abstract

2023

Bayer AL, Smolgovsky S, Ngwenyama N, Hernández-Martínez A, Kaur K, Sulka K, Amrute J, Aronovitz M, Lavine K, Sharma S, Alcaide P. 2023. T-cell MyD88 is a novel regulator of cardiac fibrosis through modulation of T-Cell activation. Circ Res. Jul 26. doi: 10.1161/CIRCRESAHA.123.323030. Abstract

Biwer LA, Lu Q, Ibarrola J, Stepanian A, Man JJ, Carvajal BV, Camarda ND, Zsengeller Z, Skurnik G, Seely EW, Ananth Karumanchi S, Jaffe IZ.2023. Smooth muscle mineralocorticoid receptor promotes hypertension after preeclampsia. Circ Res. Feb 23. doi: 10.1161/CIRCRESAHA.122.321228. Abstract

Bottom-Tanzer SF, Poyant JO, Louzada MT, Abela D, Boudouvas A, Poon E, Power L, Kim WC, Hojman HM, Bugaev N, Johnson BP, Bawazeer MA, Mahoney EJ. 2023. Longitudinal study evaluating post-ICU Syndrome differences between acute aare surgery and trauma SICU survivors. J Trauma Acute Care Surg. Jun 14. doi: 10.1097/TA.0000000000003977. Abstract

Bourgeois J, Camilli A. 2023. High-throughput mutant screening in Vibrio cholerae via transposon sequencing. Cold Spring Harb Protoc. Mar 17. doi: 10.1101/pdb.prot108185. Abstract

Bourgeois J, Camilli A. 2023. High-throughput mutant screening via transposon sequencing. Cold Spring Harb Protoc. Mar 17. doi: 10.1101/pdb.prot107867. Abstract

Chavdoula E, Anastas V, La Ferlita A, Aldana J, Carota G, Spampinato M, Soysal B, Cosentini I, Parashar S, Sircar A, Nigita G, Sehgal L, Freitas MA, Tsichlis PN..2023. Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4. Metabolism. Nov 5:155719. doi: 10.1016/j.metabol.2023.155719. Abstract

Jain A, Govindan R, Berkman AR, Luban J, Díaz-Salinas MA, Durham ND, Munro JB. 2023. Regulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome. PLoS Pathog. Dec 6;19(12):e1011848. doi: 10.1371/journal.ppat.1011848. Abstract

Kalantari P, Shecter I, Hopkins J, Pilotta Gois A, Morales Y, Harandi BF, Sharma S, Stadecker MJ. 2023. The balance between gasdermin D and STING signaling shapes the severity of schistosome immunopathology. Proc Natl Acad Sci USA. Mar 28;120(13):e2211047120. doi: 10.1073/pnas.2211047120. Abstract

Louie JD, Bromberg BH, Zunitch MJ, Schwob JE. 2023. Horizontal basal cells self-govern their neurogenic potential during injury-induced regeneration of the olfactory epithelium. Development. Jun 1:dev.201552. doi: 10.1242/dev.201552. Abstract

Matos-Rodrigues G, Hisey JA, Nussenzweig A, Mirkin SM. 2023. Detection of alternative DNA structures and its implications for human disease. Mol Cell. Oct 19;83(20):3622-3641. doi: 10.1016/j.molcel.2023.08.018. Abstract

Paquette AF, Carbone BE, Vogel S, Israel E, Maria SD, Patil NP, Sah S, Chowdhury D, Kondratiuk I, Labhart B, Morrow AL, Phillips SC, Kuang C, Hondmann D, Pandey N, Biederer T. 2023. The human milk component myo-inositol promotes neuronal connectivity. Proc Natl Acad Sci USA. Jul 25;120(30):e2221413120. doi: 10.1073/pnas.2221413120. Abstract

Perera G, Power L, Larson A, Codden CJ, Awata J, Batorsky R, Strathdee D, Chin MT. 2023. Single cell transcriptomic analysis in a mouse model of Barth Syndrome reveals cell-specific alterations in gene expression and intercellular communication. Int J Mol Sci. Jul 18;24(14):11594. doi: 10.3390/ijms241411594. Abstract

Ramirez JM, Calderon-Zavala AC, Balaram A, Heldwein EE. 2023. In vitro reconstitution of herpes simplex virus 1 fusion identifies low pH as a fusion co-trigger. mBio. Oct 24:e0208723. doi: 10.1128/mbio.02087-23. Abstract

Smalley JL, Cho N, Ng SFJ, Choi C, Lemons AHS, Chaudry S, Bope CE, Dengler JS, Zhang C, Rasband MN, Davies PA, Moss SJ. 2023. Spectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses. Commun Biol. Jan 5;6(1):11. doi: 10.1038/s42003-022-04381-x. Abstract

Smolgovsky S, Bayer AL, Kaur K, Sanders E, Aronovitz M, Filipp ME, Thorp EB, Schiattarella GG, Hill JA, Blanton RM, Cubillos-Ruiz JR, Alcaide P. 2023. Impaired T cell IRE1α-XBP1 signaling directs inflammation in experimental heart failure with preserved ejection fraction. J Clin Invest. Oct 24:e171874. doi: 10.1172/JCI171874. Abstract

Sylvia SM, Toppo AJ, Perrone GS, Miltenberg B, Power LH, Richmond JC, Salzler MJ. 2023. Revision soft-tissue allograft anterior cruciate ligament reconstruction is associated with lower patient-reported outcomes compared with primary anterior cruciate ligament reconstruction in patients aged 40 and older. Arthroscopy. doi: 10.1016/j.arthro.2022.06.035. Abstract

Toppo AJ, Perrone GS, Sylvia SM, Miltenberg BH, Power LH, Richmond JC, Salzler MJ. 2023. High levels of Satisfaction and adequate patient-reported outcomes after operative reconstruction of multiligament knee injury with allograft among patients aged 40 years and older. Arthrosc Sports Med Rehabil. Dec 16;5(1):e29-e34. doi: 10.1016/j.asmr.2022.09.012. Abstract

Van N, Degefu YN, Leus PA, Larkins-Ford J, Klickstein J, Maurer FP, Stone D, Poonawala H, Thorpe CM, Smith TC 2nd, Aldridge BB. 2023. Novel synergies and isolate specificities in the drug interaction landscape of Mycobacterium abscessus. Antimicrob Agents Chemother. Jun 6:e0009023. doi: 10.1128/aac.00090-23. Abstract

Wang Y, Travers RJ, Farrell A, Lu Q, Bays JL, Stepanian A, Chen C, Jaffe IZ. 2023. Differential vascular endothelial cell toxicity of established and novel BCR-ABL tyrosine kinase inhibitors. PLoS One. Nov 20;18(11):e0294438. doi: 10.1371/journal.pone.0294438. Abstract

Wu SC, Grace M, Munger K. 2023. The HPV8 E6 protein targets the Hippo and Wnt signaling pathways as part of its arsenal to restrain keratinocyte differentiation. mBio. Sep 7:e0155623. doi: 10.1128/mbio.01556-23. Abstract

Zunitch MJ, Fisch AS, Lin B, Barrios-Camacho CM, Faquin WC, Tachie-Baffour Y, Louie JD, Jang W, Curry WT, Gray ST, Lin DT, Schwob JE, Holbrook EH. 2023. Molecular evidence for olfactory neuroblastoma as a tumor of malignant globose basal cells. Mod Pathol. Feb 2;36(5):100122. Abstract

2022

Ameroso D, Meng A, Chen S, Felsted J, Dulla CG, Rios M. 2022. Astrocytic BDNF signaling within the ventromedial hypothalamus regulates energy homeostasis. Nat Metab. May 2. doi: 10.1038/s42255-022-00566-0. Abstract

Bayer AL, Pietruska J, Farrell J, McRee S, Alcaide P, Hinds PW. 2022. AKT1 is required for a complete palbociclib-induced senescence phenotype in BRAF-V600E-driven human melanoma. Cancers. Jan 23;14(3):572. doi: 10.3390/cancers14030572. Abstract

Bloomer H, Khirallah J, Li Y, Xu Q. 2022. CRISPR/Cas9 ribonucleoprotein-mediated genome and epigenome editing in mammalian cells. Adv Drug Deliv Rev. 81:114087. doi: 10.1016/j.addr.2021.114087. Abstract

Bottom-Tanzer S, Dulla C. 2022. Keeping up with KCNQ2: A new model of epileptic encephalopathy. Epilepsy Curr. Mar 11;22(2):141-143. doi: 10.1177/15357597221082485. Abstract

Camarda N, Travers R, Yang VK, London C, Jaffe IZ. 2022. VEGF receptor inhibitor-induced hypertension: emerging mechanisms and clinical implications. Curr Oncol Rep. Feb 18. doi: 10.1007/s11912-022-01224-0. Abstract

Choi C, Smalley JL, Lemons AHS, Ren Q, Bope CE, Dengler JS, Davies PA, Moss SJ. 2022. Analyzing the mechanisms that facilitate the subtype-specific assembly of γ-aminobutyric acid type A receptors. Front Mol Neurosci. Oct 3;15:1017404. doi: 10.3389/fnmol.2022.1017404. Abstract

Donnelly ML, Shrestha S, Ribis JW, Kuhn P, Krasilnikov M, Alves Feliciano C, Shen A. 2022. Development of a dual-fluorescent-reporter system in Clostridioides difficile reveals a division of labor between virulence and transmission gene expression. mSphere. 31:e0013222. doi: 10.1128/msphere.00132-22. Abstract

Heller-Trulli D, Liu H, Mukherjee S, Moore CL.2022. UBE3D regulates mRNA 3'-end processing and maintains adipogenic potential in 3T3-L1 ells. Mol Cell Biol. Dec 15;42(12):e0017422. doi: 10.1128/mcb.00174-22. Abstract.

Johnson MA, Klickstein JA, Khanna R, Gou Y; Cure VCP Disease Research Consortium, Raman M. 2022. The Cure VCP Scientific Conference 2021: Molecular and clinical insights into neurodegeneration and myopathy linked to multisystem proteinopathy-1 (MSP-1). Neurobiol Dis. Apr 8:105722. doi: 10.1016/j.nbd.2022.105722. Abstract

Liou YH, Personnaz J, Jacobi D, Knudsen NH, Chalom MM, Starost KA, Nnah IC, Lee CH. 2022. Hepatic Fis1 regulates mitochondrial integrated stress response and improves metabolic homeostasis. JCI Insight. Feb 22;7(4):e150041.doi: 10.1172/jci.insight.150041. Abstract

Liu H, Heller-Trulli D, Moore CL. 2022. Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal. iScience. 2022 Jul 20;25(8):104804. doi: 10.1016/j.isci.2022.104804. Abstract

Morales Y, Smyth E, Zubiago J, Bearnot B, Wurcel AG. 2022. "They just assume that we're all going to do the wrong thing with it. It's just not true": Stakeholder perspectives about peripherally inserted central catheters in people who inject drugs. Open Forum Infect Dis. Oct 19;9(10):ofac364. doi: 10.1093/ofid/ofac364. Abstract

Nishijima H, Zunitch MJ, Yoshida M, Kondo K, Yamasoba T, Schwob JE, Holbrook EH. 2022. Rapid fluorescent vital imaging of olfactory epithelium. iScience. Apr 8;25(5):104222. doi: 10.1016/j.isci.2022.104222. Abstract

Norman M, Gilboa T, Walt DR. 2022. High-sensitivity single molecule array assays for pathological isoforms in Parkinson's disease. Clin Chem. 68: 431-440. Abstract

Pataki Z, Rebolledo Viveros A, Heldwein EE. 2022. Herpes simplex virus 1 entry glycoproteins form complexes before and during membrane fusion. mBio. Aug 16:e0203922. doi: 10.1128/mbio.02039-22. Abstract

Pataki Z, Sanders EK, Heldwein EE. 2022. A surface pocket in the cytoplasmic domain of the herpes simplex virus fusogen gB controls membrane fusion. PLoS Pathog. Jun 29;18(6):e1010435. doi: 10.1371/journal.ppat.1010435. Abstract

Puri S, Kenyon BM, Hamrah P. 2022. Immunomodulatory role of neuropeptides in the cornea. Biomedicines. 10(8):1985. doi: 10.3390/biomedicines10081985. Abstract

Shuey MM, Xiang RR, Moss ME, Carvajal BV, Wang Y, Camarda N, Fabbri D, Rahman P, Ramsey J, Stepanian A, Sebastiani P, Wells QS, Beckman JA, Jaffe IZ. 2021. Systems approach to integrating preclinical apolipoprotein E-knockout investigations reveals novel etiologic pathways and master atherosclerosis network in humans. Arterioscler Thromb Vasc Biol. 42: 35-48. Abstract

Williams L, Bagley J, Iacomini J. 2022. The role of IL-6 in hyperlipidemia induced accelerated rejection. Am J Transplant. 22: 427-437. Abstract

Wolter NL, Jaffe IZ. 2022. Emerging vascular cell-specific roles for mineralocorticoid receptor: implications for understanding sex differences in cardiovascular disease. Am J Physiol Cell Physiol. Nov 28. doi: 10.1152/ajpcell.00372.2022. Abstract

2021

Anastasiou M, Newton GA, Kaur K, Carrillo-Salinas FJ, Smolgovsky SA, Bayer AL, Ilyukha V, Sharma S, Poltorak A, Luscinskas FW, Alcaide P. 2021. Endothelial STING controls T-cell transmigration in an IFN-I dependent manner. JCI Insight. 22:149346. doi: 10.1172/jci.insight.149346. Abstract

Bayer AL, Alcaide P. 2021. MyD88: At the heart of inflammatory signaling and cardiovascular disease. J Mol Cell Cardiol. Aug 6:S0022-2828(21)00154-1. doi: 10.1016/j.yjmcc.2021.08.001. Abstract

Biwer LA, Carvajal BV, Lu Q, Man JJ, Jaffe IZ. 2021. Mineralocorticoid and estrogen receptors in endothelial cells coordinately regulate microvascular function in obese female mice. Hypertension. 3:HYPERTENSIONAHA12016911. doi: 10.1161/HYPERTENSIONAHA.120.16911. Abstract

Bottom-Tanzer SF, Poyant JO, Louzada MT, Ahmed SE, Boudouvas A, Poon E, Hojman HM, Bugaev N, Johnson BP, Van Kirk A, Daniel E, Emoff C, Mahoney EJ. 2021. High occurrence of post intensive care syndrome identified in surgical ICU survivors after implementation of a multidisciplinary clinic. J Trauma Acute Care Surg. doi: 10.1097/TA.0000000000003231. Abstract

Eidell KP, Lovy A, Sylvain NR, Scangarello FA, Muendlein HI, Ophir MJ, Nguyen K, Seminario MC, Bunnell SC. 2021. LFA-1 and Kindlin-3 enable the collaborative transport of SLP-76 microclusters by myosin and dynein motors. J Cell Sci. 19:jcs.258602. doi: 10.1242/jcs.258602. Abstract

Goodwill AG, Baker HE, Dick GM, McCallinhart PE, Bailey CA, Brown SM, Man JJ, Tharp DL, Clark HE, Blaettner BS, Jaffe IZ, Bowles DK, Trask AJ, Tune JD, Bender SB. 2021. Mineralocorticoid receptor blockade normalizes coronary resistance in obese swine independent of functional alterations in Kv channels. Basic Res Cardiol. 116(1):35. doi: 10.1007/s00395-021-00879-3. Abstract

Jamali A, Kenyon BM, Ortiz G, Bayraktutar BN, Sendra VG, Hamrah P. 2021. Topical adoptive transfer of plasmacytoid dendritic cells for corneal wound healing. Methods Mol Biol. 2193: 159-174. Abstract

Jamali A, Kenyon B, Ortiz G, Abou-Slaybi A, Sendra VG, Harris DL, Hamrah P. 2021. Plasmacytoid dendritic cells in the eye. Prog Retin Eye Res. 24:100877. doi: 10.1016/j.preteyeres.2020.100877. Abstract

Kim SK, Biwer LA, Moss ME, Man JJ, Aronovitz MJ, Martin GL, Carrillo-Salinas FJ, Salvador AM, Alcaide P, Jaffe IZ. 2021. Mineralocorticoid receptor in smooth muscle contributes to pressure overload-induced heart failure. Circ Heart Fail. Feb 1:CIRCHEARTFAILURE120007279. doi: 10.1161/CIRCHEARTFAILURE.120.007279. Abstract

Man JJ, Lu Q, Elizabeth Moss M, Carvajal B, Baur W, Garza AE, Freeman R, Anastasiou M, Ngwenyama N, Adler GK, Alcaide P, Jaffe IZ. 2021. Myeloid mineralocorticoid receptor transcriptionally regulates P-Selectin glycoprotein ligand-1 and promotes monocyte trafficking and atherosclerosis. Arterioscler Thromb Vasc Biol. 41: 2740-2755. Abstract

Menon DP, Qi G, Kim SK, Moss ME, Penumatsa KC, Warburton RR, Toksoz D, Wilson J, Hill NS, Jaffe IZ, Preston IR. 2021. Vascular cell-specific roles of mineralocorticoid receptors in pulmonary hypertension. Pulm Circ. Jun 18;11(3):20458940211025240. doi: 10.1177/20458940211025240. Abstract

Mukkavalli S, Klickstein JA, Ortiz B, Juo P, Raman M. 2021. The p97-UBXN1 complex regulates aggresome formation. J Cell Sci. Mar 12:jcs.254201. doi: 10.1242/jcs.254201. Abstract

Murray LP, Govindan R, Mora AC, Munro JB, Mace CR. 2021. Antibody affinity as a driver of signal generation in a paper-based immunoassay for Ebola virus surveillance. Anal Bioanal Chem. 413: 3695-3706. Abstract

Neil AJ, Hisey JA, Quasem I, McGinty RJ, Hitczenko M, Khristich AN, Mirkin SM. 2021. Replication-independent instability of Friedreich's ataxia GAA repeats during chronological aging. Proc Natl Acad Sci USA 118(5):e2013080118. doi: 10.1073/pnas.2013080118. Abstract

Nilles EJ, Karlson EW, Norman M, Gilboa T, Fischinger S, Atyeo C, Zhou G, Bennett CL, Tolan NV, Oganezova K, Walt DR, Alter G, Simmons DP, Schur P, Jarolim P, Woolley A, Baden LR. 2021. Evaluation of three commercial and two non-commercial immunoassays for the detection of prior infection to SARS-CoV-2. J Appl Lab Med. Jul 1:jfab072. doi: 10.1093/jalm/jfab072. Abstract

Norman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR. 2021. L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma. Nat Methods. 18: 631-634. Abstract

Pace JR, Lampkin BJ, Abakah C, Moyer A, Miao J, Deprey K, Cerulli RA, Lin YS, Baleja JD, Baker D, Kritzer JA. 2021. Stapled β-hairpins featuring 4-mercaptoproline. J Am Chem Soc. Sep 13. doi: 10.1021/jacs.1c04378. Abstract

Park L, Luth ES, Jones K, Hofer J, Nguyen I, Watters KE, Juo P. 2021. The Snail transcription factor CES-1 regulates glutamatergic behavior in C. elegans. PLoS One 16(2):e0245587. doi: 10.1371/journal.pone.0245587. Abstract

Qiu M, Li Y, Bloomer H, Xu Q. 2021. Developing biodegradable lipid nanoparticles for intracellular mRNA delivery and genome editing. Acc Chem Res. 2021 Oct 20. doi: 10.1021/acs.accounts.1c00500. Abstract

Ter-Ovanesyan D, Norman M, Lazarovits R, Trieu W, Lee JH, Church GM, Walt DR. 2021. Framework for rapid comparison of extracellular vesicle isolation methods. Elife. Nov 16;10:e70725. doi: 10.7554/eLife.70725. Abstract

Trombetta BA, Kandigian SE, Kitchen RR, Grauwet K, Webb PK, Miller GA, Jennings CG, Jain S, Miller S, Kuo Y, Sweeney T, Gilboa T, Norman M, Simmons DP, Ramirez CE, Bedard M, Fink C, Ko J, De León Peralta EJ, Watts G, Gomez-Rivas E, Davis V, Barilla RM, Wang J, Cunin P, Bates S, Morrison-Smith C, Nicholson B, Wong E, El-Mufti L, Kann M, Bolling A, Fortin B, Ventresca H, Zhou W, Pardo S, Kwock M, Hazra A, Cheng L, Ahmad QR, Toombs JA, Larson R, Pleskow H, Luo NM, Samaha C, Pandya UM, De Silva P, Zhou S, Ganhadeiro Z, Yohannes S, Gay R, Slavik J, Mukerji SS, Jarolim P, Walt DR, Carlyle BC, Ritterhouse LL, Suliman S. 2021. Evaluation of serological lateral flow assays for severe acute respiratory syndrome coronavirus-2. BMC Infect Dis. Jun 16;21(1):580. doi: 10.1186/s12879-021-06257-7. Abstract

Wolter NL, LeClair MJ, Chin MT. 2021. Plasma metabolomic profiling of hypertrophic cardiomyopathy patients before and after surgical myectomy suggests postoperative improvement in metabolic function. BMC Cardiovasc Disord. 28;21(1):617. doi: 10.1186/s12872-021-02437-0. Abstract

Wu SC, Münger K. 2021. Role and clinical utility of cancer/testis antigens in head and neck squamous cell carcinoma. Cancers. Nov 14;13(22):5690. doi: 10.3390/cancers13225690. Abstract

Yavuz Saricay L, Bayraktutar BN, Kenyon BM, Hamrah P. 2021. Concurrent ocular pain in patients with neurotrophic keratopathy. Ocul Surf. 22:143-151. Abstract

2020

Bulow U, Govindan R, Munro JB. 2020. Acidic pH triggers lipid mixing mediated by Lassa virus GP. Viruses 12(7) pii: E716. doi: 10.3390/v12070716. Abstract

Bourgeois J, Lazinski DW, Camilli A. 2020. Identification of spacer and protospacer sequence requirements in the Vibrio cholerae Type I-E CRISPR/Cas system. mSphere 5(6):e00813-20. doi: 10.1128/mSphere.00813-20. Abstract

Carbone BE, Abouleish M, Watters KE, Vogel S, Ribic A, Schroeder OH, Bader BM, Biederer T. 2020. Synaptic connectivity and cortical maturation are promoted by the ω-3 fatty acid docosahexaenoic acid. Cereb Cortex. 30: 226-240. Abstract

Cerulli RA, Shehaj L, Tosic I, Jiang K, Wang J, Frank DA, Kritzer JA. 2020. Cytosolic delivery of peptidic STAT3 SH2 domain inhibitors. Bioorg Med Chem. 28: 115542. Abstract

Cerulli RA, Kritzer JA. 2020. Phosphotyrosine isosteres: past, present and future. Org Biomol Chem. 18: 583-605. Abstract

Cerulli RA, Shehaj L, Brown HF, Pace JR, Mei Y, Kritzer JA. 2020. Stapled peptide inhibitors of autophagy adapter LC3B. Chembiochem. doi: 10.1002/cbic.202000212. Abstract

Das DK, Bulow U, Diehl WE, Durham ND, Senjobe F, Chandran K, Luban J, Munro JB. 2020. Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding. PLoS Biol. 18(2):e3000626. doi: 10.1371/journal.pbio.3000626. Abstract

Dickson D, Stohn P, Rodriguez LS, Hernandez A, Harrington A, Liaw L, Feig LA. 2020. Involvement of early embryonic miR-409-3p in the establishment of anxiety levels in female mice. Dev Neurobiol. doi: 10.1002/dneu.22756. Abstract

Donnelly ML, Forster ER, Rohlfing AE, Shen A. 2020. Differential effects of "resurrecting" Csp pseudoproteases during Clostridioides difficile spore germination. Biochem J. pii: BCJ20190875. doi: 10.1042/BCJ20190875. Abstract

Durham ND, Howard AR, Govindan R, Senjobe F, Fels JM, Diehl WE, Luban J, Chandran K, Munro JB. 2020. Real-time analysis of individual Ebola virus glycoproteins reveals pre-fusion, entry-relevant conformational dynamics. Viruses. 12(1). pii: E103. doi: 10.3390/v12010103. Abstract

Jamali A, Seyed-Razavi Y, Chao C, Ortiz G, Kenyon B, Blanco T, Harris DL, Hamrah P. 2020. Intravital multiphoton microscopy of the ccular surface: Alterations in conventional dendritic cell morphology and kinetics in dry eye disease. Front Immunol.11:742. Abstract

Jin SX, Dickson D, Maguire J, Feig LA. 2020. Ras-GRF1 in CRF cells controls the early adolescent female response to repeated stress. J Endocrinol. 245: 397-410. Abstract

Klickstein JA, Mukkavalli S, Raman M. 2020. AggreCount: An unbiased image analysis tool for identifying and quantifying cellular aggregates in a spatially-defined manner. J Biol Chem. 20:jbc.RA120.015398. doi: 10.1074/jbc.RA120.015398. Abstract

Krolewski RC, Lin B, Stampfer S, Packard A, Schwob JE. 2020. A group of olfactory receptor alleles that encode full length proteins are down-regulated as olfactory sensory neurons mature. Sci Rep. 10(1):1781. doi: 10.1038/s41598-020-58779-w. Abstract

Lee SD, Liu HY, Graber JH, Heller-Trulli D, Kaczmarek Michaels K, Cerezo JF, Moore CL. 2020. Regulation of the Ysh1 endonuclease of the mRNA cleavage/polyadenylation complex by ubiquitin-mediated degradation. RNA Biol. doi: 10.1080/15476286.2020.1724717. Abstract

Man JJ, Beckman JA, Jaffe IZ. 2020. Sex as a biological variable in atherosclerosis. Circ Res. 126: 1297-1319. Abstract

Muendlein HI*, Sarhan J*, Liu BC, Connolly WM, Schworer SA, Smirnova I, Tang AY, Ilyukha V, Pietruska J, Tahmasebi S, Sonenberg N, Degterev A, Poltorak A. 2020. Constitutive interferon attenuates RIPK1/3-mediated cytokine translation. Cell Rep. 30: 699-713. * Equal contribution. Abstract

Norman M, Gilboa T, Ogata AF, Maley AM, Cohen L, Cai Y, Zhang J, Feldman JE, Hauser BM, Caradonna TM, Chen B, Schmidt AG, Alter G, Charles RC, Ryan ET, Walt DR. 2020. Ultra-sensitive high-resolution profiling of anti-SARS-CoV-2 antibodies for detecting early seroconversion in COVID-19 patients. medRxiv. May 2:2020.04.28.20083691. Abstract

Nilles EJ, Karlson EW, Norman M, Gilboa T, Fischinger S, Atyeo C, Zhou G, Bennett CL, Tolan NV, Oganezova K, Walt DR, Alter G, Simmons DP, Schur P, Jarolim P, Baden LR. 2020. Evaluation of two commercial and two non-commercial immunoassays for the detection of prior infection to SARS-CoV-2. medRxiv. Jun 26:2020.06.24.20139006. Abstract

Norman M, Gilboa T, Ogata AF, Maley AM, Cohen L, Busch EL, Lazarovits R, Mao CP, Cai Y, Zhang J, Feldman JE, Hauser BM, Caradonna TM, Chen B, Schmidt AG, Alter G, Charles RC, Ryan ET, Walt DR. 2020. Ultrasensitive high-resolution profiling of early seroconversion in patients with COVID-19. Nat Biomed Eng. 4: 1180-1187. Abstract

Ogata AF, Maley AM, Wu C, Gilboa T, Norman M, Lazarovits R, Mao CP, Newton G, Chang M, Nguyen K, Kamkaew M, Zhu Q, Gibson TE, Ryan ET, Charles RC, Marasco WA, Walt DR. 2020. Ultra-sensitive serial profiling of SARS-CoV-2 antigens and antibodies in plasma to understand disease progression in COVID-19 patients with severe disease. Clin Chem. 8:hvaa213. doi: 10.1093/clinchem/hvaa213. Abstract

Ortiz G, Chao C, Jamali A, Seyed-Razavi Y, Kenyon B, Harris DL, Zoukhri D, Hamrah P. 2020. Effect of dry eye disease on the kinetics of lacrimal gland dendritic cells as visualized by intravital multi-photon microscopy. Front Immunol. 11:1713.doi: 10.3389/fimmu.2020.01713. Abstract

Ozawa M, Davis P, Ni J, Maguire J, Papouin T, Reijmers L. 2020. Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction. Nat Commun.11: 4358. doi: 10.1038/s41467-020-18199-w. Abstract

Pietras CM, Power L, Slonim DK. 2020. aTEMPO: Pathway-specific temporal anomalies for precision therapeutics. Pac Symp Biocomput. 25:683-694. Abstract

White EM, Stampfer SD, Heldwein EE. 2020. Expression, purification, and crystallization of HSV-1 glycoproteins for structure determination. Methods Mol Biol. 2060: 377-393. Abstract

2019

Bagley J, Williams L, Hyde M, Birriel CP, Iacomini J. 2019. Hyperlipidemia and allograft rejection. Curr Transpl Rep. 6: 90–98. Abstract

Cerulli RA, Kritzer JA. 2019. Stringing together a universal influenza antibody. Biochemistry 58: 1943-1944. Abstract

Coleman JH, Lin B, Louie JD, Peterson J, Lane RP, Schwob JE. 2019. Spatial determination of neuronal diversification in the olfactory epithelium. J Neurosci. 39: 814-832. Abstract

Gross KM*, Zhou W*, Breindel JL, Ouyang J, Jin DX, Sokol ES, Gupta PB, Huber K, Zou L, Kuperwasser C. 2019. Loss of Slug compromises DNA damage repair and accelerates stem cell aging in mammary epithelium. Cell Rep. 28: 394-407. (*equal contribution) Abstract

Gupta PB, Pastushenko I, Skibinski A, Blanpain C, Kuperwasser C. 2019. Phenotypic plasticity: Driver of cancer initiation, progression, and therapy resistance. Cell Stem Cell 24: 65-78. Abstract

Holloway JR, Williams ZH, Freeman MM, Bulow U, Coffin JM. 2019. Gorillas have been infected with the HERV-K (HML-2) endogenous retrovirus much more recently than humans and chimpanzees. Proc Natl Acad Sci USA. 116: 1337-1346. Abstract

Koenig JB, Cantu D, Low CS, Sommer ME, Noubary F, Croker D, Whalen M, Kong D, Dulla CG. 2019. Glycolytic inhibitor 2-deoxyglucose prevents cortical hyperexcitability after traumatic brain injury. J CI Insight 5. pii: 126506. doi: 10.1172/jci.insight.126506. Abstract

Manohar A, Rossini L, Colvert G, Vigneault DM, Contijoch F, Chen MY, Del Alamo JC, McVeigh ER. 2019. Regional dynamics of fractal dimension of the left ventricular endocardium from cine computed tomography images. J Med Imaging. 6: 046002. Abstract

Moss ME, Carvajal B, Jaffe IZ. 2019. The endothelial mineralocorticoid receptor: Contributions to sex differences in cardiovascular disease. Pharmacol Ther. Nov;203:107387. doi: 10.1016/j.pharmthera.2019.06.009. Abstract

Moss ME, Lu Q, Iyer SL, Engelbertsen D, Marzolla V, Caprio M, Lichtman AH, Jaffe IZ. 2019. Endothelial mineralocorticoid receptors contribute to vascular inflammation in atherosclerosis in a sex-specific manner. Arterioscler Thromb Vasc Biol. 39: 1588-1601. Abstract

Peterson J, Lin B, Barrios-Camacho CM, Herrick DB, Holbrook EH, Jang W, Coleman JH, Schwob JE. 2019. Activating a reserve neural stem cell population in vitro enables engraftment and multipotency after transplantation. Stem Cell Reports. 12: 680-695. Abstract

Rohlfing AE, Eckenroth BE, Forster ER, Kevorkian Y, Donnelly ML, Benito de la Puebla H, Doublié S, Shen A. 2019. The CspC pseudoprotease regulates germination of Clostridioides difficile spores in response to multiple environmental signals. PLoS Genet. 15: e1008224. Abstract

Sarhan J, Liu BC, Muendlein HI, Weindel CG, Smirnova I, Tang AY, Ilyukha V, Sorokin M, Buzdin A, Fitzgerald KA, Poltorak A. 2019. Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis. Cell Death Differ. 26: 332-347. Abstract

Sarhan J, Mikailov A. 2019. Comment on "Developing an international standard for the classification of surface anatomic location for use in clinical practice and epidemiologic research." J Am Acad Dermatol. pii: S0190-9622(19)32814-2. doi: 10.1016/j.jaad.2019.09.065. Abstract

Sarrafpour S, Saleh D, Ayoub S, Radcliffe N. 2019. Micropulse transscleral cyclophotocoagulation: A look at long term effectiveness and outcomes. Ophthalmol Glaucoma, in press. DOI: https://doi.org/10.1016/j.ogla.2019.02.002.

Sekulovic O, Bourgeois J, Shen A, Camilli A. 2019. Expanding the repertoire of conservative site-specific recombination in Clostridioides difficile. Anaerobe Dec;60:102073. doi: 10.1016/j.anaerobe.2019.102073. Abstract

Schluchter A, Jan C, Lowe K, Vigneault DM, Contijoch F, McVeigh ER. 2019. Vascular landmark-based method for highly reproducible measurement of left atrial appendage volume in computed tomography. Circ Cardiovas Imaging. 12(12):e009075. doi: 10.1161/CIRCIMAGING.119.009075. Abstract

Vigneault DM, Yang E, Jensen PJ, Tee MW, Farhad H, Chu L, Noble JA, Day SM, Colan SD, Russell MW, Towbin J, Sherrid MV, Canter CE, Shi L, Ho CY, Bluemke DA. 2019. Left ventricular strain is abnormal in preclinical and overt hypertrophic cardiomyopathy: Cardiac MR feature tracking. Radiology. 29: 640-648. Abstract

Zhou W, Herwald SE, McCarthy C, Uppot RN, Arellano RS. 2019. Radiofrequency ablation, cryoablation and microwave ablation for T1a renal cell carcinoma: A comparative evaluation of therapeutic and renal function outcomes. J Vasc Interv Radiol. 32: 544-547. Abstract

Zhou W, Gross KM, Kuperwasser C. 2019. Molecular regulation of Snai2 in development and disease. J Cell Sci. 132(23). pii: jcs235127. doi: 10.1242/jcs.235127. Abstract

2018

Child KM, Herrick DB, Schwob JE, Holbrook EH, Jang W. 2018. The neuroregenerative capacity of olfactory stem cells is not limitless: Implications for aging. J Neurosci. 38: 6806-6824. Abstract

Das DK, Govindan R, Nikić-Spiegel I, Krammer F, Lemke EA, Munro JB. Direct visualization of the conformational dynamics of single influenza hemagglutinin trimers. Cell 174: 926-937. Abstract

Davel AP, Lu Q,Moss ME, Rao S, Anwar IJ, DuPont JJ, Jaffe IZ. 2018. J Am Heart Assoc 7: pii: e007675. doi: 10.1161/JAHA.117.007675. Abstract

Davis P, Reijmers LG. 2018. The dynamic engram: fear memories and the basolateral amygdala. Brain Res Bull. 141: 44-49.  Abstract

Dickson DA, Paulus JK, Mensah V, Lem J, Saavedra-Rodriguez L, Gentry A, Pagidas K, Feig LA. 2018. Reduced levels of miRNAs 449 and 34 in sperm of mice and men exposed to early life stress. Transl Psychiatry 8: 101. Abstract

Dixon T, Cohen E, Cairns DM, Rodriguez M, Mathews J, Jose R, Kaplan DL. 2018. Bioinspired 3D human neuromuscular junction development in suspended hydrogel arrays. Tissue Eng Part C Methods 24: 346-359. Abstract

Gopal S, Lu Q,Man JJ, Baur W, Rao SP, Litichevskiy L, Papanastasiou M, Creech AL, DeRuff KC, Mullahoo J, Officer A, Egri SB, Davison D, Jaffe JD, Jaffe IZ. 2018. A phosphoproteomic signature in endothelial cells predicts vascular toxicity of tyrosine kinase inhibitors used in CML. Blood Adv. 2: 1680-1684. Abstract

Fiaturi N, Russo JW, Nielsen HC, Castellot JJ Jr. 2017. CCN5 in alveolar epithelial proliferation and differentiation during neonatal lung oxygen injury. J Cell Commun Signal. 12: 217-229. Abstract

Herrick DB, Tanenbaum JE, Mankarious M, Vallabh S, Fleischman E, Kurra S, Burke SM, Roguski M, Mroz TE, Lavelle WF, Florman JE, Riesenburger RI. 2018. The relationship between surgical site drains and reoperation for wound-related complications following posterior cervical spine surgery: a multicenter retrospective study. J Neursurg Spine 14: 1-7. Abstract

Herrick DB, Guo Z, Jang W, Schnittke N, Schwob JE. 2018. Canonical Notch signaling directs the fate of differentiating neurocompetent progenitors in the mammalian olfactory epithelium. J Neurosci. 38: 5022-5037. Abstract

Koenig JB, Dulla CG 2018. Dysregulated glucose metabolism as a therapeutic target to reduce post-traumatic epilepsy. Front Cell Neurosci. doi: 10.3389/fncel.2018.00350. Abstract

Koenig J, Dulla C 2018. Complements to the chef: Are microglia eating neurons in the epileptic brain? Epilepsy Curr. 18: 128-130. Abstract

Ledoux T, Aridgides D, Salvador R, Ngwenyama N, Panagiotidou S, Alcaide P, Blanton R, Perrin MA. 2018. Trypanosoma cruzi neurotrophic factor facilitates cardiac repair in a mouse model of chronic Chagas disease. J Pharmacol Exp Ther. 368: 11-20. Abstract

Lewis JB, Scangarello FA, Murphy JM, Eidell KP, Sodipo MO, Ophir MJ, Sargeant R, Seminario MC, Bunnell SC. 2018. ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters. J Cell Sci. 131. doi: 10.1242/jcs.215517. Abstract

Liu BC, Sarhan J, Poltorak A. 2018. Host-intrinsic interferon status in infection and immunity. Trends Mol Med. 24: 658-668. Abstract

Hui Mingalone CK, Liu Z, Hollander JM, Garvey KD, Gibson AL, Banks RE, Zhang M, McAlindon TE, Nielsen HC, Georgakoudi I, Zeng L. 2018. Bioluminescence and second harmonic generation imaging reveal dynamic changes in the inflammatory and collagen landscape in early osteoarthritis. Lab Invest. 98: 656-669. Abstract

Kalantari P, Morales Y, Miller EA, Jaramillo LD, Ponichtera HE, Wuethrich MA, Cheong C, Seminario MC, Russo JM, Bunnell SC, Stadecker MJ. 2018. CD209a synergizes with Dectin-2 and mincle to drive severe Th17 cell-mediated schistosome egg-induced immunopathology. Cell Rep. 22: 1288-1300. Abstract

Kim SK, McCurley AT, DuPont JJ, Aronovitz M, Moss ME, Stillman IE, Karumanchi SA, Christou DD, Jaffe IZ. 2018. Smooth muscle cell-mineralocorticoid receptor as a mediator of cardiovascular stiffness with aging. Hypertension 71: 609-621. Abstract

Liu BC, Sarhan J, Panda A, Muendlein HI, Ilyukha V, Coers J, Yamamoto M, Isberg RR, Poltorak A. 2018. Constitutive interferon maintains GBP expression required for release of bacterial components upstream of pyroptosis and anti-DNA responses. Cell Rep. 24: 155-168. Abstract

Moss ME, DuPont JJ, Iyer SL, McGraw AP, Jaffe IZ. 2018. No significant role for smooth muscle cell mineralocorticoid receptors in atherosclerosis in the apolipoprotein-E knockout mouse model. Front Cardiovasc Med. 5:81. Abstract

Neil AJ, Liang MU, Khristich AN, Shah KA, Mirkin SM. 2018. RNA-DNA hybrids promote the expansion of Friedreich's ataxia (GAA)n repeats via break-induced replication. Nucleic Acids Res. 46: 3487-3497. Abstract

Pirone A, Alexander JM, Koenig JB, Cook-Snyder DR, Palnati M, Wickham RJ, Eden L, Shrestha N, Reijmers L, Biederer T, Miczek KA, Dulla CG, Jacob MH. 2018. Social stimulus causes aberrant activation of the medial prefrontal cortex in a mouse model with autism-like behaviors. Fron Synaptic Neurosci. 10: 35. Abstract

Rodriguez MJ, Dixon TA, Cohen E, Huang W, Omenetto FG, Kaplan DL. 2018. 3D freeform printing of silk fibroin. Acta Biomater. 71: 379-387. Abstract

Saleh D, Degterev A. 2018. Chemical library screens to identify pharmacological modulators of necroptosis. Methods Mol Biol. 1857: 19-33. Abstract

Sarhan J, Liu BC, Muendlein HI, Li P, Nilson R, Tang AY, Rongvaux A, Bunnell SC, Shao F, Green DR, Poltorak A. 2018. Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection. Proc Natl Acad Sci USA. 115: E10888-E10897. Abstract

Sekulovic O, Mathias Garrett E, Bourgeois J, Tamayo R, Shen A, Camilli A. 2018. Genome-wide detection of conservative site-specific recombination in bacteria. PLoS Genet. 14: e10007332. Abstract

Zhou W, Herwald SE, Uppot RN, Arellano RS. 2018. Risk assessment of chronic kidney disease following microwave ablation for stage T1 renal cell carcinoma. J Vasc Interv Radio. 29: 1685-1691. Abstract

Zhou W, Herwald SE, Uppot RN, Arellano RS. 2018. Image-guided thermal ablation for non-resectable recurrence of renal cell cancer following nephrectomy: Clinical experience with eleven patients. Cardiovasc Intervent Radiol. 41: 1743-1750. Abstract

Vigneault DM, Pourmorteza A, Thomas ML, Bluemke DA, Noble JA. 2018. SiSSR: Simultaneous subdivision surface registration for the quantification of cardiac function from computed tomography in canines. Med Image Anal. 46: 215-228. Abstract

Vigneault DM, Xie W, Ho CY, Bluemke DA, Noble JA. 2018. Ω-Net (Omega-Net): Fully automatic, multi-view cardiac MR detection, orientation, and segmentation with deep neural networks. Med Image Anal. 48: 95-106. Abstract

von Mässenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, Bach S, Schiessl IM, Nogusa S, Balachandran S, Anders HJ, Ting AT, Bleich M, Degterev A, Kunzelmann K, Bornstein SR, Green DR, Hugo C, Linkermann A. 2018. Phenytoin inhibits necroptosis. Cell Death Dis. 9:359. Abstract