Jake Jinkun Chen, D.M.D., M.D.S., Ph.D., F.A.C.D.
(617) 636-2729
Research/Areas of Interest:
1. Gene expression and regulation in bone development and formation using transgenics, gene knockouts, signal transduction pathway, and epigenetic including microRNA and long noncoding RNA;
2. Using adult stem cells and induced pluripotent stem cells (iPSCs) to engineer and regenerate tissues;
3. Translational studies including treatment for bone disorders in diabetic and obese patients, bone metastasis of breast cancer, association of dental diseases with systemic disorders, e.g., Alzheimer's disease and osteoarthritis, and osseointegration of bone implants;
4. Application of nanomaterials in cell-based gene therapy.
Education
- Doctor of Medicine in Dentistry (DMD), Tufts University School of Dental Medicine, Boston, United States
- Master of Dental Science (MDS), University of Connecticut Health Center, Farmington, United States
- Doctor of Philosophy (PhD), University of Toronto, Canada