Aritra Nath Chattopadhyay

Research/Areas of Interest

My research focuses on developing platforms that allow real-time monitoring of physiological activity in cells. The core of biomedical research involves measuring changes in the levels of specific biomolecules in cells or tissue samples. The current methods used to detect biomolecules – ELISAs, Western blots, immunofluorescence – are generally endpoint assays, and they report up or down regulation of biomolecules losing out on important temporal information. In my research, I propose to develop a modular turn-on biosensor platform that will measure the rates of phenotypic changes of desired biomolecules in real time, in multiple tissues and across multiple pathways. This new capability that will also measure the duration of the effect and the kinetics of the rebound once the effect diminishes, all in one simple experiment.

Advisor: Joshua Kritzer, PhD