From PREP to PhD: Ashley Luo’s Journey at Tufts GSBS

Ashley Luo, a graduate of Tufts University’s Post-baccalaureate Research Internship (PREP) program, offers a glimpse into her academic journey—a journey marked by curiosity, determination, and growth. As a first-generation, low-income student, Ashley initially faced challenges in navigating the academic landscape, but her story is one of resilience and discovery. In this interview, she shares how the PREP program not only helped her transition into graduate school but also equipped her with the skills and confidence to succeed in the world of scientific research.
Why did you choose to pursue this degree?
"My curiosity has always driven me towards a path in scientific research, even if I didn’t know how to navigate it. As a first-generation low-income college student, it took extra work to even figure out how the academic system worked and what opportunities were available to me. By the time I finished undergrad, I found myself wanting to pursue a research career, but I felt like I needed more time to figure out how to achieve that goal. I found out about PREP through a previous mentor and thought it would perfectly bridge the gap between me and graduate school."
Why did you choose Tufts to pursue your degree?
"I had the privilege of previously working with Dr. Andrew Camilli, and through that research experience, I was introduced to and welcomed by the Tufts community—specifically the Molecular Microbiology department. What I loved was how close-knit everyone was and how committed each person was to the success of their peers. The location of Tufts in the heart of Chinatown and Downtown Boston also appealed to me. The city is full of students, making it a comfortable place for growth and discovery. But most importantly, the success of the Tufts PREP program and what it offers solidified my decision. The program offers a glimpse into graduate student life, providing research experience, courses, writing workshops, and opportunities to present at conferences. I felt it was well-structured to prepare me for graduate school."
What is the focus of your research, and what questions are you trying to answer?
"My research focused on bacteriophages (phages)—viruses that infect bacteria. Phages and bacteria co-evolve, and one key area of interest is the CBASS system, an anti-phage defense mechanism in bacteria. I investigated why virulent Vibrio cholerae phages were resistant to CBASS, even though they should have been countered by the bacteria’s immune system. The phage protein ICP3, found in a virulent V. cholerae phage, seemed to antagonize CBASS. My questions revolved around understanding whether this protein had two functions—one related to DNA injection and another to CBASS antagonism—and how it interacted with the bacterial immune system."
Describe your experience in the program.
"The PREP program was one of the most significant experiences in my academic career. I conducted a meaningful research project and gained increasing independence as the year progressed. I learned how to balance lab work and coursework and navigated the graduate school application process. I also grew more confident in presenting my research at several conferences. This program bridged all the gaps I had before starting, and I strongly recommend it to anyone who is uncertain about their next steps after undergrad."
What was your favorite aspect about the program?
"What I enjoyed most about PREP was the opportunity to forge meaningful connections within the Tufts community. The social events hosted by graduate student organizations and the Molecular Microbiology department allowed me to interact with faculty and students in a relaxed environment. The close-knit atmosphere was special, and I especially appreciated the shared experience of navigating the grad school application process with fellow PREP students from similar backgrounds."
What are some of your favorite ways to recharge outside of the lab or classroom?
"Outside of research, I balance my scientific pursuits with creativity, particularly in art and cosplaying. Boston hosts fun annual conventions like Fan Expo and Anime Boston, which I love attending. There’s also the King Richard’s Renaissance Faire, though it’s a bit outside of the city. Boston's proximity to other cities is a bonus—I enjoy exploring places like Salem during Halloween or heading to Providence, Rhode Island for the weekend. The city also has numerous parks and nature trails, perfect for a reset."
What is your proudest academic/professional accomplishment while at Tufts?
"My proudest accomplishment was getting accepted to several top graduate schools and ultimately becoming a Molecular Microbiology PhD student at Tufts! I credit this success to my training in the PREP program. I also became more independent as a scientist and honed my communication skills, having presented my research at various conferences like the Symposium on the Immune System of Bacteria and the New England PREP Symposium."
How has completion of the program helped you advance your professional goals?
"Completing the PREP program gave me the skills, confidence, and experience necessary to succeed in the graduate school application process and to secure a position as a PhD student in Molecular Microbiology. The program prepared me to be more independent in my research and provided me with the necessary tools to present and communicate my work effectively."
What do you want a prospective student to know about Tufts?
"Tufts is an incredibly supportive environment for academic and professional growth. As a former PREP student and now a PhD student, I can say that both programs are strong, well-structured, and dedicated to the success of their students. The Tufts community, combined with the location in Boston, was a huge factor in my decision to pursue my graduate education here. I’ve found it to be an ideal place to nurture both academic curiosity and career development."
Related Links:
Molecular Microbiology
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