Research/Areas of Interest: My research program centers on the characterization of metabolic pathways and the determination of three-dimensional structures of proteins using Nuclear Magnetic Resonance (NMR) spectroscopy. The structures are used to help understand the mechanisms by which these proteins function, to design proteins with desired properties, and to select low molecular weight compounds that inhibit protein-protein interactions. The small molecule quantification in various models of cancer and other diseases are used to highlight metabolic perturbations for potential biomarker discovery.
- Bachelor of Science, Biochemistry, University of Manitoba, Canada, 1983
- Master of Science, Chemistry, University of Manitoba, Winnipeg, Canada, 1994
- Doctor of Philosophy, Biochemistry, University of Alberta, Canada, 1990