Immunology Featured in Research Spotlight
Work from the Alcaide lab, lead by Jay Ngwenyama, a fourth year Immunology PhD student has shed new light on the way CD4+ T cells, become activated and recruited to the heart to mediate adverse cardiac remodeling. This work advances our understanding of heart failure.
Check out Jay's papers.
Ngwenyama N, Salvador AM, Velázquez F, Nevers T, Levy A, Aronovitz MJ, Luster AD, Huggins GS, Alcaide P. 2019. CXCR3 regulates CD4+ T cell cardiotropism in pressure overload induced cardiac dysfunction. JCI Insight Epub ahead of print. Abstract
Nevers T, Salvador AM, Velazquez F, Ngwenyama N, Carrillo-Salinas FJ, Aronovitz M, Blanton RM, Alcaide P. 2017. Th1 effector T cells selectively orchestrate cardiac fibrosis in nonischemic heart failure. J Exp Med. 214: 3311-3329. Abstract