Age-related macular degeneration (AMD) is an irreversible destruction of the central area of the retina, called the macula. As many as 11 million Americans have some form of macular degeneration and it is a leading cause of vision loss and irreversible blindness in Americans aged 60 and older. The Kumar-Singh lab has developed a non-viral delivery system that could be used to deliver therapeutics for AMD and Retinitis Pigmentosa effectively. My project focuses on using this system with a cell penetrating peptide called POD to deliver an anti-apoptotic protein to retinal cells to offer protection against retinal degeneration. I will be measuring efficiency of the protein delivery and its function.