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Graduate School of Biomedical Sciences

Davis Vigneault

MD, PhD Student
Davis Vigneault

Davis Vigneault

MD, PhD Student

Education: 
BS, Biochemistry, Tufts University, Medford, MA
Research synopsis: 

I completed my PhD in the NIH Partnership Program where I studied with David Bluemke and Alison Noble.

My work centered on evaluation of cardiac function, which currently relies upon global parameters such as ejection fraction, myocardial mass, and cardiac output. These are all insensitive and non-specific parameters that may not become aberrant until late in the disease course. Regional functional parameters, such as cardiac strain, strain rate, twist, and torsion may provide additional information for prognosis and the guiding of treatment.  Methods for measuring regional functional parameters have been developed, but have not yet reached the clinic due to prolonged acquisition and analysis times.  My project focused on the development of a software application that ideally derives these parameters from standard cine cardiac magnetic resonance images and analyzes them in an automated fashion.  This approach would accelerate both the acquisition and analysis, making it easier to translate this modality to the clinic.

I am now completing the fourth year of medical school.