My thesis research, conducted with Peter Juo, PhD, used C. elegans as a model system to study the nervous system and synapse transmission. I focuses on studying the regulation of the glutamate receptor glr-1. Glutamate receptors are critical receptors for excitatory neurotransmission. The regulation of their activity and levels at the synapse is important for synaptic plasticity events such as learning and memory, while their impaired regulation is implicated in various neurological diseases such as depression, spinal cord injury, and ALS. I currently am looking at different transcription factors and signaling pathways that regulate glr-1.
I am now completing my fourth year of medical school.