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Graduate School of Biomedical Sciences

Brigett Carvajal

PREP Scholar
BA, Psychology, City University of New York - Hunter College, New York, NY
Research synopsis: 

My project explores the consequences of endothelial mineralocorticoid receptor (EC-MR) activation during cardiovascular disease. In particular, females are disproportionately affected by EC-MR activation in the setting of obesity and high cholesterol, exacerbating endothelial cell damage. My goal is to determine the sex-dependent mechanisms by which EC-MR contributes to cardiovascular dysfunction in the presence of cardiovascular disease risk factors, thereby determining more effective therapeutic targets for women and men.