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Graduate School of Biomedical Sciences

Angela Capriglione

Research Technician

angela capriglione

Angela Capriglione

Research Technician

Education: 
BS, Neurobiology, Simmons University, Boston, MA
Research synopsis: 

In Alzheimer’s Disease (AD), the clearance of beta-amyloid from the central nervous system is impaired. It is hypothesized that reduction in beta-amyloid clearance is due, at least in part, to age-dependent impairments in the glymphatic pathway. My research focuses on targeting glial cells to manipulate gene expression in mouse models of Alzheimer’s to determine by what mechanisms beta-amyloid clearance is modulated. By gaining a better understanding of glial biology and the glymphatic pathway, there is the potential to develop strategies to reduce the burden of AD.

Advisor: