The cell’s ability to launch an innate immune response often depends on that cell's and neighboring cells’ ability to recognize initial infection. Detecting cytosolic bacterial or viral DNA is accomplished through the protein cGAS. cGAS binding to DNA and subsequent association with the ER-bound protein STING ultimately leads to an inflammatory response. My research focuses on identifying what DNA species are recognized by this pathway and understanding how that complex translocates to the ER. I am also interested in the role of STING in thymic involution and metabolism with age.