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Graduate School of Biomedical Sciences

Tate Tabtieng

Postdoctoral Scholar

Tate Tabtieng

Tate Tabtieng

Postdoctoral Scholar

Education: 
BE, Bioengineering, University of Pennsylvania, Philadelphia, PA
PhD, Biochemistry, Graduate School of Biomedical Sciences, Tufts University, Boston, MA
Research synopsis: 

Kaposi’s sarcoma-associated herpesvirus (KSHV) is a herpesvirus that infects B lymphocytes and endothelial cells, and causes tumors in immunocompromised patients. Like other herpesviruses, KSHV undergoes cycles of latent and lytic infection. Reactivation of KSHV into the lytic cycle is an essential process for tumor formation. To accomplish lytic reactivation, KSHV must avoid innate cellular immune responses. My research focuses on the role of caspases in circumventing the antiviral immune response and promote lytic reactivation. Understanding the mechanisms behind lytic reactivation of KSHV can provide key insights for therapies to block tumor development.

Advisor: