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Graduate School of Biomedical Sciences

Shruti Sharma

Assistant Professor of Immunology
Shruti Sharma

Shruti Sharma

Assistant Professor of Immunology

Office phone: 617-636-0470
Lab phone: 617-636-6612
Campus: Boston
Office: Jaharis 813
Jaharis 501
BSc, Microbiology & Biotechnology, R Ruia College
MSc, Biotechnology, University of Mumbai
PhD, Cell Biology & Immunology, University of Maryland - College Park
Postdoctoral Training, University of Massachusetts Medical School
Research synopsis: 

My lab focuses on the innate immune response to nucleic acids from microbial sources as well as from ourselves. Specifically, we are evaluating the role of pathways that sense nucleic acids to shape host metabolism, tissue remodeling, fibrosis and wound healing responses. A particular focus of the lab is to understand the contribution of intracellular DNA sensing to immune-homeostasis. Using a combination of hypothesis driven and unbiased next gen approaches we hope to clarify the signaling nodes engaged during homeostasis. The physiological impact of the pathways we discover will be tested in models of inflammation including infections, autoimmunity, aging and neurodegenerative diseases. These studies will directly impact our understanding of resolution of inflammation in all settings.

Lab members: