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Graduate School of Biomedical Sciences

Recent Publications from the Gridley Lab

Peterson SM, Turner JE, Harrington A, Davis-Knowlton J, Lindner V, Gridley T, Vary CPH, Liaw L. 2018. Notch2 and proteomic signatures in mouse neointimal lesion formation. Arterioscler Thromb Vasc Biol. Epub ahead of print. Abstract

Basch ML, Brown RM, Jen HI, Semerci F, Depreux F, Edlund RK, Zhang H, Norton CR, Gridley T, Cole SE, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves AK. 2016. Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife 5. pii: e19921. doi: 10.7554/eLife.19921.  Abstract

Gridley T. 2016. Twenty years in Maine: Integrating insights from developmental biology into translational medicine in a small state. Curr Top Dev Biol. 116: 435-443.  Abstract

Krebs LT, Norton CR, Gridley T. 2016. Notch signal reception is required in vascular smooth muscle cells for ductus arteriosus closure. Genesis 54:86-90.  Abstract

Rostama B, Turner JE, Seavey GT, Norton CR, Gridley T, Vary CP, Liaw L. 2015. DLL4/Notch1 and BMP9 interdependent signaling induces human endothelial cell quiescence via P27KIP1 and thrombospondin-1. Arterioscler Thromb Vasc Biol. 35: 2626-2637.  Abstract

Pardo-Saganta A, Tata PR, Law BM, Saez B, Chow RD, Prabhu M, Gridley T, Rajagopal J. 2015. Parent stem cells can serve as niches for their daughter cells. Nature 523: 597-601.  Abstract

Horvay K, Jardé T, Casagranda F, Perreau VM, Haigh K, Nefzger CM, Akhtar R, Gridley T, Berx G, Haigh JJ, Barker N, Polo JM, Hime GR, Abud HE. 2015. Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium. EMBO J. 34: 1319-1335.  Abstract

Zander MA, Cancino GI, Gridley T, Kaplan DR, Miller FD. 2014. The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life. PLoS One 9: e104767.  Abstract

Gridley T, Kajimura S. 2014. Lightening up a notch: Notch regulation of energy metabolism. Nat Med. 20: 811-812.  Abstract

Gridley T, Groves AK. 2014. Overview of genetic tools and techniques to study Notch signaling in mice. methods Mol Biol. 1187: 47-61.  Abstract

Norton CR, Chen Y, Han XH, Bradley CK, Krebs LT, Yoon JK, Gridley T. 2013. Absence of a major role for the snai1 and snai3 genes in regulating skeletal muscle regeneration in mice. PLoS Curr. pii: doi: 10.1371/  Abstract

Bradley CK, Norton CR, Chen Y, Han X, Booth CJ, Yoon JK, Krebs LT, Gridley T. 2013. The snail family gene snai3 is not essential for embryogenesis in mice. PLoS One 8: e65344.  Abstract

Chen Y, Gridley T. 2013. The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis. Biochem Biophys Res Commun. 435: 356-360.  Abstract

Costa MJ, Wu X, Cuervo H, Srinivasan R, Bechis SK, Cheang E, Marjanovic O, Gridley T, Cvetic CA, Wang RA. 2013. Notch4 is required for tumor onset and perfusion. Vasc Cell. 5: 7.   Abstract

Van de Walle I, Waegemans E, De Medts J, De Smet G, De Smedt M, Snauwaert S, Vandekerckhove B, Kerre T, Leclercq G, Plum J, Gridley T, Wang T, Koch U, Radtke F, Taghon T. 2013. Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength. J Exp Med. 210: 683-697.  Abstract

Tran IT, Sandy AR, Carulli AJ, Ebens C, Chung J, Shan GT, Radojcic V, Friedman A, Gridley T, Shelton A, Reddy P, Samuelson LC, Yan M, Siebel CW, Maillard I. 2013. Blockade of individual Notch ligands and receptors controls graft-versus-host disease. J Clin Invest. 123: 1590-1604.  Abstract

Xu J, Gridley T. 2013. Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles. BMC Biol 11: 13.  Abstract

Chen Y, Gridley T. 2013. Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 28: 1412-1421.  Abstract